TB-500: What It Is, How It Works & Research Data | QSC
QSC RESEARCH COMPOUND
TB-500
Thymosin Beta-4 peptide studied for tissue repair and actin polymerisation.
≥99% HPLC Purity MS Confirmed Janoshik COA Research Use Only
What is TB-500?
TB-500 is a synthetic analog of Thymosin Beta-4 (Tβ4) — a 43-amino acid ubiquitous intracellular peptide that regulates actin polymerisation. The active fragment (amino acids 17-23) contains the LKKTETQ actin-binding domain.
How Does TB-500 Work?
LKKTETQ domain sequesters G-actin monomers, shifting the G-actin:F-actin equilibrium and promoting actin cytoskeletal remodelling. Promotes cell migration, angiogenesis via KGF and VEGF upregulation, and reduces myosin light chain kinase expression.
TB-500 is a synthetic analog of Thymosin Beta-4 (Tβ4) — a 43-amino acid ubiquitous intracellular peptide that regulates actin polymerisation. The active fragment (amino acids 17-23) contains the LKKTETQ actin-binding domain.
How does TB-500 work?
LKKTETQ domain sequesters G-actin monomers, shifting the G-actin:F-actin equilibrium and promoting actin cytoskeletal remodelling. Promotes cell migration, angiogenesis via KGF and VEGF upregulation, and reduces myosin light chain kinase expression.
QSC stocks research-grade TB-500 at ≥99% HPLC purity with Janoshik COA verification. Available in Lyophilised powder, 10mg vial kits with 5-region domestic US and international shipping.
What compounds are related to TB-500?
Researchers studying TB-500 frequently also investigate: BPC-157, BPC-157+TB-500 Blend, GHK-Cu.
Research Use Only: All QSC products are sold strictly for in vitro laboratory research. Not for human or veterinary use. Researchers are responsible for compliance with local regulations.
