What is Vorijohn 200mg (VORICONAZOLE)?
Broad-spectrum triazole antifungal for invasive aspergillosis (first-line), invasive candidiasis, scedosporiosis, fusariosis, and other serious invasive fungal infections.
How it Works
Inhibits fungal CYP51 (lanosterol demethylase), blocking ergosterol biosynthesis. Broader spectrum than fluconazole — covers important mold species.
Quick Specs
| Form | Oral tablets — pre-dosed |
| Active Ingredient | VORICONAZOLE |
| Dose per Tablet | 200MG |
| Pack Size | 102 tablets |
| Storage | Room temperature (15–25°C), cool dry place |
| Shelf Life | 2–3 years (properly stored) |
Common Side Effects
Visual disturbances (transient photopsia, color changes — very common, usually harmless), photosensitivity, elevated LFTs, hallucinations (elderly), QT prolongation.
Safety Warnings
⚠️ Multiple major CYP450 interactions (inhibits CYP2C19, 2C9, 3A4) — contraindicated with rifampin, carbamazepine, sirolimus. Therapeutic drug monitoring recommended. Prolonged use associated with squamous cell carcinoma.
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