HGH Fragment 176-191 5mg | 10-Vial Kit | Lipolytic Peptide

🇺🇸 1-Region Domestic Shipping
HGH Fragment 176-191 5mg | 10-Vial Kit — GH C-terminal fragment (residues 176-191) — activates β3-adrenergic receptors to drive fat oxidation without activating growth hormone receptor (GHR) or stimulating IGF-1. ≥99% HPLC purity, MS confirmed, Janoshik COA. Research use only.

🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days

$220

or
SKU: QSC-FR5-HGHFRAG176191-5MG-10VIAL
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What is HGH Fragment 176-191?

HGH Fragment 176-191 (Native GH C-terminal fragment — lipolytic peptide) is a 16-amino acid native GH C-terminal fragment. Native C-terminal fragment of human growth hormone (residues 176-191) activating lipolysis via beta-3 adrenergic receptor without GH receptor binding. Adipose-selective lipolytic activity identical mechanistic pathway to AOD-9604 but using the native (non-Tyr modified) sequence.

Research Applications

Native GH Fragment Research

Structure-activity comparison using native vs modified (AOD-9604) sequence

Beta-3 AR Lipolysis

Adipocyte HSL activation, triglyceride hydrolysis, FFA release

No GHR Activation

Adipose-selective activity — no IGF-1, no anabolic GH effects

vs AOD-9604

Native (Frag 176-191) vs modified (Tyr + 177-191) research design

Adipose Biology

Fat cell lipolysis mechanism in adipose tissue models

Quick Specs

Form Lyophilized powder
Purity ≥99% by HPLC — every batch
CAS Number 12629-01-5
Molecular Formula C₈₆H₁₄₄N₂₆O₂₈S
Peptide Type Synthetic Peptide / Growth Hormone Fragment
Identity MS molecular weight confirmed — every batch
COA Janoshik-independent, publicly verifiable
Manufacture In-house Fmoc SPPS — Qingdao, China
Storage -20°C sealed | 2–8°C reconstituted (2–4 weeks)
Shelf Life 24 months unopened

Certificate of Analysis (COA)

Frequently Asked Questions

How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this QSC compound and how is it verified?
All QSC compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
🧪 Peptide Research Tools: Use QSC’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
🧬 PubMed Research — Fragment
Search PubMed ↗
183,428 publications found Last 10 years 3 most recent shown

Showing 3 of 183,428 for Fragment

View all on PubMed ↗

Source: PubMed / NCBI  ·  Last 10 years  ·  Refreshed every 24 hours  ·  For research reference only — not clinical guidance.

⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION

QSC products are strictly for in vitro and in vivo laboratory research. Not intended for diagnostic, therapeutic, or personal use.

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Research Use Disclaimer

All QSC products are strictly for laboratory, scientific, and research use only. They are not for human consumption, medical treatment, diagnosis, or disease prevention.

By purchasing or using QSC products, you confirm:

  • You are a qualified researcher or acting under the supervision of one.
  • Products will only be used for legitimate research purposes.
  • Products are not evaluated by the FDA or any regulatory authority for human use.
  • You assume all responsibility for legal compliance, proper handling, and storage.
  • You meet the legal age requirement in your jurisdiction.
No Warranty: Products are sold “as is,” with no express or implied warranties regarding efficacy, safety, or suitability. Results in research may vary. QSC is not responsible for outcomes, interpretations, or conclusions drawn from any studies conducted using these products.
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General Safety & Handling

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Not for Human Use

These compounds are for research only. Any off-label, personal, or clinical use is strictly outside the intended scope of supply.

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PPE Required

Always use appropriate personal protective equipment (gloves, lab coat, eye protection) when handling peptides.

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Storage Compliance

Follow product-specific storage conditions to maintain identity, purity, and biological activity.

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Proper Disposal

Dispose of all materials in accordance with institutional biosafety, chemical waste, and hazardous material protocols.

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Verify Quality

Janoshik COAs are available on every product page. Verify batch identity (MS confirmed) and purity (≥99% HPLC) before use.

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Peptide Storage Guidelines

🌑 Light-protected💧 Low moisture🌡️ Stable temperature🔬 Sterile handling

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