What is Jaknat 10mg (RUXOLITINIB)?
JAK1/JAK2 inhibitor for myelofibrosis, polycythemia vera, graft-versus-host disease, and alopecia areata. Jakavi brand most widely available internationally.
How it Works
Inhibits JAK1/JAK2 in the JAK/STAT pathway — reduces pro-inflammatory cytokine signaling and abnormal hematopoietic cell proliferation.
Quick Specs
| Form | Oral tablets — pre-dosed |
| Active Ingredient | RUXOLITINIB |
| Dose per Tablet | 10MG |
| Pack Size | 10×10 (100 tablets) |
| Storage | Room temperature (15–25°C), cool dry place |
| Shelf Life | 2–3 years (properly stored) |
Common Side Effects
Anemia, thrombocytopenia, neutropenia, infections, weight gain, bruising, non-melanoma skin cancer risk.
Safety Warnings
⚠️ Dose reduction in hepatic/renal impairment. TB screening before starting. Live vaccines contraindicated. Gradual tapering required. Interrupt for serious infections.
🌏 International shipping: 7–14 days
