NAD+: What It Is, How It Works & Research Data | QSC
QSC RESEARCH COMPOUND
NAD+
Nicotinamide adenine dinucleotide — central metabolic coenzyme and longevity research compound.
≥99% HPLC Purity MS Confirmed Janoshik COA Research Use Only
What is NAD+?
NAD+ (nicotinamide adenine dinucleotide) is the oxidised form of the essential coenzyme involved in >500 metabolic reactions as a hydride acceptor and donor. Concentrations decline ~50% between ages 20–60. Supplementation/injection research focuses on restoring NAD+ to youthful levels via IV/subcutaneous administration.
How Does NAD+ Work?
NAD+ is required by: sirtuins (SIRT1-7, longevity deacetylases), PARP enzymes (DNA repair), CD38 (NAD+ consuming enzyme elevated in inflammation), and as the central electron carrier in glycolysis and the TCA cycle. Declining NAD+ impairs all of these simultaneously.
Key Research
NAD+ IV infusion studies: cognitive function improvements, fatigue reduction, and mitochondrial functional restoration in ageing models. Preclinical data on sirtuin-mediated lifespan extension (Guarente lab). CD38 inhibition as strategy to preserve NAD+ levels.
NAD+ (nicotinamide adenine dinucleotide) is the oxidised form of the essential coenzyme involved in >500 metabolic reactions as a hydride acceptor and donor. Concentrations decline ~50% between ages 20–60. Supplementation/injection research focuses on restoring NAD+ to youthful levels via IV/subcutaneous administration.
How does NAD+ work?
NAD+ is required by: sirtuins (SIRT1-7, longevity deacetylases), PARP enzymes (DNA repair), CD38 (NAD+ consuming enzyme elevated in inflammation), and as the central electron carrier in glycolysis and the TCA cycle. Declining NAD+ impairs all of these simultaneously.
What research has been done on NAD+?
NAD+ IV infusion studies: cognitive function improvements, fatigue reduction, and mitochondrial functional restoration in ageing models. Preclinical data on sirtuin-mediated lifespan extension (Guarente lab). CD38 inhibition as strategy to preserve NAD+ levels.
Where can I buy research-grade NAD+?
QSC stocks research-grade NAD+ at ≥99% HPLC purity with Janoshik COA verification. Available in Injectable vials, multiple concentrations with 5-region domestic US and international shipping.
Research Use Only: All QSC products are sold strictly for in vitro laboratory research. Not for human or veterinary use. Researchers are responsible for compliance with local regulations.
