HGH (Somatropin): What It Is, How It Works & Research Data | QSC
QSC RESEARCH COMPOUND
HGH (Somatropin)
Recombinant human growth hormone studied for GH axis biology and metabolic research.
≥99% HPLC Purity MS Confirmed Janoshik COA Research Use Only
What is HGH (Somatropin)?
Human Growth Hormone (somatropin) is a 191-amino acid single-chain polypeptide produced by somatotroph cells in the anterior pituitary. Recombinant HGH is produced via rDNA technology in E. coli or CHO cells. Acts via GHR (JAK2/STAT5 pathway) and indirectly via IGF-1.
How Does HGH (Somatropin) Work?
GHR binding → JAK2 dimerisation → STAT5b phosphorylation → hepatic IGF-1 gene transcription. Direct lipolytic effects on adipocytes via HSL. Anti-insulin effects on glucose metabolism. Protein synthesis promotion in muscle via IGF-1 mediation.
Key Research
Multiple Phase 3 datasets in GH deficiency (adult and paediatric), Turner syndrome, Prader-Willi. AGHD studies establish body composition, bone density, and metabolic improvements with rhGH.
Related Compounds
Researchers studying HGH (Somatropin) frequently also investigate: Sermorelin, CJC-1295, Ipamorelin, IGF-1 LR3, GHRP-2. View the complete QSC Research Manual →
Frequently Asked Questions
What is HGH (Somatropin)?
Human Growth Hormone (somatropin) is a 191-amino acid single-chain polypeptide produced by somatotroph cells in the anterior pituitary. Recombinant HGH is produced via rDNA technology in E. coli or CHO cells. Acts via GHR (JAK2/STAT5 pathway) and indirectly via IGF-1.
How does HGH (Somatropin) work?
GHR binding → JAK2 dimerisation → STAT5b phosphorylation → hepatic IGF-1 gene transcription. Direct lipolytic effects on adipocytes via HSL. Anti-insulin effects on glucose metabolism. Protein synthesis promotion in muscle via IGF-1 mediation.
What research has been done on HGH (Somatropin)?
Multiple Phase 3 datasets in GH deficiency (adult and paediatric), Turner syndrome, Prader-Willi. AGHD studies establish body composition, bone density, and metabolic improvements with rhGH.
Where can I buy research-grade HGH (Somatropin)?
QSC stocks research-grade HGH (Somatropin) at ≥99% HPLC purity with Janoshik COA verification. Available in Lyophilised powder, 10 IU, 36 IU, 100 IU vial kits with 5-region domestic US and international shipping.
Research Use Only: All QSC products are sold strictly for in vitro laboratory research. Not for human or veterinary use. Researchers are responsible for compliance with local regulations.
