Epitalon vs Thymalin vs Pinealon — Khavinson Peptide Comparison
QSC Research Guide
Epitalon vs Thymalin vs Pinealon — Khavinson Peptide Comparison
Epitalon, Thymalin, and Pinealon are the three primary Khavinson peptide bioregulators — each targeting a specific organ system (pineal, immune/thymic, and pineal respectively) for lifespan and healthspan research.
Side-by-Side Comparison
Attribute
Epitalon
Thymalin
Pinealon
Mechanism class
AEDG tetrapeptide — telomerase activator
Thymus polypeptide bioregulator
EDR tripeptide — pineal bioregulator
Receptor targets
Telomerase (hTERT), pineal melatonin
T-cell maturation, immune restoration
Pinealocyte gene expression, melatonin
Half-life
Unknown
Short
Unknown
Key advantage
hTERT telomerase activation — telomere length restoration. Melatonin normalisation via pinealocytes. Most studied Khavinson peptide
Epitalon is the most studied with the most compelling telomerase and lifespan extension data. Thymalin addresses the immune aspect of aging (thymic involution and immunosenescence). Pinealon targets pineal circadian function — often combined with Epitalon for comprehensive pineal/telomere coverage in longevity protocols.
Frequently Asked Questions
What is the difference between Epitalon and Pinealon?
Both are Khavinson peptides with pineal activity, but different mechanisms. Epitalon (AEDG tetrapeptide) activates telomerase (hTERT) and has broader anti-aging evidence. Pinealon (EDR tripeptide) specifically modulates pinealocyte gene expression for melatonin synthesis. They are often combined as complementary pineal-axis bioregulators.
What does Thymalin add to an Epitalon protocol?
Epitalon addresses telomere/pineal aging; Thymalin addresses immune aging (thymic involution). Age-related decline affects both pathways — Thymalin restores T-cell immune surveillance that Epitalon does not directly target. In Khavinson longevity protocols, both are typically included.
Is there human clinical data for Epitalon?
Yes. Russian gerontological studies (Khavinson, St. Petersburg) include human administration data showing reduced mortality over 12+ year follow-up periods in older adults. The quality of this data by Western clinical trial standards is lower than FDA-grade RCTs — researchers should review Khavinson’s published papers directly.
Research Use Only: All QSC compounds are sold strictly for laboratory research purposes only. Not for human consumption, veterinary use, or any other application. Researchers are responsible for compliance with local regulations.
QSC Network
Compound reference, COA verification, and regional warehouse information across the QSC network.
