QSC PHARMA GRADE
🇮🇳 India Warehouse100-Count Pack
What is Colchiheal 0.5mg (COLCHICINE)?
Gout (acute flares and prevention), familial Mediterranean fever, pericarditis, and cardiovascular event reduction in coronary artery disease (proven in COLCOT and LoDoCo2 trials).
How it Works
Binds tubulin dimers inhibiting microtubule polymerization — prevents neutrophil chemotaxis to inflamed joints. Blocks NLRP3 inflammasome and IL-1beta release.
Quick Specs
| Form | Oral tablets — pre-dosed |
| Active Ingredient | COLCHICINE |
| Dose per Tablet | 0.5MG |
| Pack Size | 10×10 (100 tablets) |
| Storage | Room temperature (15–25°C), cool dry place |
| Shelf Life | 2–3 years (properly stored) |
Common Side Effects
GI effects (diarrhea, nausea, vomiting — dose-limiting), myopathy and neuropathy with prolonged use. Bone marrow suppression (rare at low doses).
Safety Warnings
⚠️ Low therapeutic index — potentially life-threatening toxicity if overdosed (no antidote). Significant interactions with CYP3A4/P-gp inhibitors (macrolides, statins, cyclosporine — dose reduction needed). Renal and hepatic dose adjustment.
