QSC RESEARCH GRADE
≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SynthesisChina Warehouse
What is Tesofensine?
Tesofensine is a triple monoamine reuptake inhibitor — blocks serotonin, noradrenaline, and dopamine transporters (SERT/NET/DAT). Studied for central appetite suppression, energy expenditure upregulation, and as a potent weight-loss research tool. Active metabolite NS2360 contributes to pharmacological activity. Research use only.
Research Applications
Triple Reuptake Inhibition
SERT/NET/DAT inhibition pharmacology, synaptic monoamine elevation, transporter Ki
Central Appetite Suppression
Hypothalamic monoamine signalling — satiety, food intake reduction models
Energy Expenditure
Sympathomimetic-like metabolic rate increase, thermogenesis, resting energy
Dopaminergic Research
DAT inhibition — dopamine system, reward pathway, locomotor activity
Metabolic Disease Research
Obesity models, weight loss pharmacology, body composition
Quick Specs
| Form | Raw bulk powder (crystalline/amorphous) |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 195875-84-4 |
| Molecular Formula | C₁₇H₂₃ClN₂O₂, MW 326.8 |
| Identity | MS molecular weight confirmed — every batch |
| Compound Type | Triple Monoamine Reuptake Inhibitor (SNRI + DRI) |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house synthesis — Qingdao, China |
| Storage | Room temperature sealed | cool, dry storage |
| Shelf Life | 24 months (unopened) |
