QSC RESEARCH GRADE
≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SynthesisChina Warehouse
What is MK-677 (Ibutamoren)?
MK-677 (Ibutamoren) is an orally active, non-peptidic ghrelin mimetic and GH secretagogue. Activates the GHS-R1a receptor to stimulate pulsatile GH release and downstream IGF-1 production. Research tool for GH axis pharmacology, IGF-1 upregulation, sleep architecture research, and somatopause models. Research use only.
Research Applications
GHS-R1a Agonism
Ghrelin receptor activation, cAMP pathway, GH pulse amplitude/frequency
IGF-1 Axis Research
Hepatic IGF-1 production, tissue anabolism, IGF-1 downstream signalling
Oral GH Secretagogue PK
Non-peptidic oral bioavailability, plasma GH/IGF-1 kinetics, duration of action
Sleep Architecture
REM sleep enhancement, slow-wave sleep, GH nocturnal pulsatility
Body Composition Research
Lean mass, fat mass, and bone density effects of sustained GH/IGF-1 elevation
Quick Specs
| Form | Raw bulk powder (crystalline/amorphous) |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 159752-10-0 |
| Molecular Formula | C₂₈H₄₀N₄O₆S·CH₄O₃S, MW 624.8 |
| Identity | MS molecular weight confirmed — every batch |
| Compound Type | GH Secretagogue / Ghrelin Receptor Agonist |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house synthesis — Qingdao, China |
| Storage | Room temperature sealed | cool, dry storage |
| Shelf Life | 24 months (unopened) |
