QSC RESEARCH GRADE
≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SynthesisChina Warehouse
What is Anastrozole (Arimidex)?
Anastrozole (Arimidex) is a non-steroidal triazole aromatase inhibitor — reversibly blocks CYP19A1 with high selectivity. Reduces serum estradiol ~80–90% in research models. Widely used AI reference compound for estrogen suppression, aromatase pharmacology, and comparison vs steroidal AIs. Research use only.
Research Applications
Reversible Aromatase Inhibition
CYP19A1 competitive inhibition Ki, IC50, selectivity over other CYP enzymes
Estradiol Suppression Kinetics
Serum E2 reduction, dose-response, washout and recovery dynamics
Non-Steroidal vs Steroidal AI
Anastrozole vs exemestane — reversible vs irreversible, structural class differences
HPG Axis Estrogen Research
Aromatase inhibition impact on hypothalamic/pituitary ER feedback, LH/FSH
Breast Cancer Models
ER+ tumour estrogen deprivation, AI resistance mechanisms, combination studies
Quick Specs
| Form | Raw bulk powder (crystalline/amorphous) |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 120511-73-1 |
| Molecular Formula | C₁₇H₁₉N₅, MW 293.4 |
| Identity | MS molecular weight confirmed — every batch |
| Compound Type | Non-Steroidal Aromatase Inhibitor (Reversible) |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house synthesis — Qingdao, China |
| Storage | Room temperature sealed | cool, dry storage |
| Shelf Life | 24 months (unopened) |
