Alprostadil (Prostaglandin E1, PGE1) is an endogenous prostanoid that binds EP2 and EP4 receptors (Gs-coupled) to elevate cAMP, producing vasodilation, platelet aggregation inhibition, and smooth muscle relaxation. In penile tissue, PGE1 acts via EP2/EP4 on cavernous smooth muscle to produce erection independently of PDE5 pathways — making it the reference vasoactive compound for erectile pharmacology and a direct alternative to PDE5 inhibitor mechanisms. FDA-approved (Caverject, MUSE). Also studied for peripheral arterial disease, pulmonary hypertension, and ductus arteriosus patency.
Alprostadil is Prostaglandin E1, an endogenous prostanoid that activates EP2/EP4 receptors to elevate cAMP and produce vasodilation and smooth muscle relaxation. In penile tissue it produces erection via a PDE5-independent mechanism. FDA-approved for erectile dysfunction, it is used in research for vascular, erectile, pulmonary, and prostanoid receptor pharmacology.
How is Alprostadil supplied?
QSC Alprostadil is supplied as a ready-to-use injectable solution. Store at 2–8°C refrigerated and protect from light. PGE1 is unstable at room temperature — refrigerate until use.
What purity is QSC Alprostadil?
QSC Alprostadil is ≥99% HPLC pure with MS-confirmed PGE1 identity on every batch. COA verifiable at verify.janoshik.com.
Research Use Only: All QSC compounds are sold strictly for laboratory research purposes only. Not for human consumption, veterinary use, or any other application. Researchers are responsible for compliance with local regulations.
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