Cerebrolysin is a standardised porcine brain-derived neuropeptide mixture containing low-molecular-weight peptides (<10 kDa) that cross the blood-brain barrier. The active fraction contains peptide sequences with BDNF-like, NGF-like, CNTF-like, and IGF-1-like neurotrophic activity. Mechanism involves: TrkB receptor activation (BDNF pathway), TrkA receptor activation (NGF pathway), PI3K/Akt and MAPK/ERK neuroprotective signalling, and reduced glutamate excitotoxicity. Cerebrolysin has clinical trial evidence (stroke rehabilitation, Alzheimer's disease) making it among the best-characterised neuropeptide preparations. 85% amino acids, 15% peptide fragments by composition.
Research Applications
Neuroprotection
TrkB/TrkA activation for neural survival in ischaemia and excitotoxicity models
Cognitive Enhancement
BDNF/NGF pathway upregulation for synaptic plasticity and memory consolidation
Alzheimer’s Research
Amyloid reduction and tau pathology modulation — clinical trial evidence
Stroke Rehabilitation
Post-ischaemic neurogenesis and functional recovery — multiple RCTs
Neurogenesis
Adult hippocampal neurogenesis stimulation via BDNF-like peptide activity
Cerebrolysin is a standardised porcine brain-derived neuropeptide complex containing low-molecular-weight peptides that mimic BDNF, NGF, and CNTF neurotrophic activity. It crosses the BBB and activates TrkB/TrkA receptors for neuroprotection, cognitive enhancement, and neurogenesis. It has clinical evidence in stroke and Alzheimer’s research.
How is Cerebrolysin supplied?
QSC Cerebrolysin is supplied as a ready-to-use injectable solution — no reconstitution required. Store at 2–8°C refrigerated. Do not freeze. The solution is slightly yellow, which is normal for this neuropeptide complex.
What purity is QSC Cerebrolysin?
QSC Cerebrolysin maintains ≥99% HPLC purity specification with peptide profile confirmation on every batch. COA is published and verifiable at verify.janoshik.com.
Research Use Only: All QSC compounds are sold strictly for laboratory research purposes only. Not for human consumption, veterinary use, or any other application. Researchers are responsible for compliance with local regulations.
QSC Network
Compound reference, COA verification, and regional warehouse information across the QSC network.