Gonadorelin Research Hub ≥99% HPLC · Janoshik Independent COA · US-Based · Research Use Only
Gonadorelin (Gonal-F, GnRH decapeptide: pyroGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2) is the synthetic form of Gonadotropin-Releasing Hormone (GnRH). It acts on GNRHR (GnRH receptor) at the anterior pituitary to stimulate LH (luteinizing hormone) and FSH (follicle-stimulating hormone) release, activating the hypothalamic-pituitary-gonadal (HPG) axis. Research applications include HPG axis modulation, testosterone suppression models (pulsatile vs continuous dosing), fertility research, and PCT-adjacent hormonal research. QSC stocks Gonadorelin at ≥99% HPLC with Janoshik independent COA.
Gonadorelin sits at the hypothalamic-pituitary interface — upstream of LH/FSH → testosterone/estrogen production. GnRH agonist analogs (Leuprolide, Triptorelin) are long-acting; Gonadorelin is the short-acting native decapeptide form for pulsatile research protocols.
Research Applications
PCT (post-cycle therapy) research — HPG axis restoration after androgen suppression. Male fertility research — LH/FSH stimulation. Prostate cancer models — continuous dosing paradoxical suppression. Female fertility research — ovulation induction studies.
Frequently Asked Questions
What is Gonadorelin?
Gonadorelin is the synthetic form of GnRH (Gonadotropin-Releasing Hormone) — a decapeptide that activates GNRHR at the anterior pituitary to stimulate LH and FSH release. Pulsatile dosing maintains HPG axis activation; continuous dosing causes GNRHR downregulation and testosterone suppression. QSC stocks Gonadorelin at ≥99% HPLC with Janoshik COA. Research use only.
Is Gonadorelin the same as GnRH?
Yes — Gonadorelin is the INN (International Nonproprietary Name) for synthetic human GnRH (Gonadotropin-Releasing Hormone). It shares the identical amino acid sequence: pyroGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2. Clinically used analogues (Leuprolide, Buserelin, Nafarelin) are modified for extended duration; Gonadorelin is the native short-acting form.
Does QSC stock Gonadorelin?
Yes — QSC stocks Gonadorelin (GnRH decapeptide) at ≥99% HPLC with Janoshik independent COA, verifiable at verify.janoshik.com. Research use only.
Research Use Only: All QSC products sold strictly for in vitro laboratory research. Not for human or veterinary use. Information on this page is educational and does not constitute medical advice.
