MK-677 (Ibutamoren): What It Is, How It Works & Research Data | QSC
QSC RESEARCH COMPOUND
MK-677 (Ibutamoren)
Oral GHSR-1a agonist studied for GH pulse amplification and IGF-1 elevation.
≥99% HPLC Purity MS Confirmed Janoshik COA Research Use Only
What is MK-677 (Ibutamoren)?
MK-677 (Ibutamoren) is the only orally bioavailable GHSR-1a (ghrelin receptor) agonist with documented clinical data. Not a peptide — a non-peptide spiropiperidine with ~24-hour half-life enabling once-daily oral dosing. Produces sustained GH pulse amplification and IGF-1 elevation without injection.
Multiple Phase 2 trials: MK-677 25mg daily for 2 years in elderly subjects produced significant increases in lean body mass, bone density, and IGF-1 levels. Frasca et al. trial in hip fracture patients. Recognised as the most clinically validated GH secretagogue aside from GHRH analogs.
Related Compounds
Researchers studying MK-677 (Ibutamoren) frequently also investigate: Ipamorelin, CJC-1295, Sermorelin, Hexarelin, IGF-1 LR3. View the complete QSC Research Manual →
Frequently Asked Questions
What is MK-677 (Ibutamoren)?
MK-677 (Ibutamoren) is the only orally bioavailable GHSR-1a (ghrelin receptor) agonist with documented clinical data. Not a peptide — a non-peptide spiropiperidine with ~24-hour half-life enabling once-daily oral dosing. Produces sustained GH pulse amplification and IGF-1 elevation without injection.
What research has been done on MK-677 (Ibutamoren)?
Multiple Phase 2 trials: MK-677 25mg daily for 2 years in elderly subjects produced significant increases in lean body mass, bone density, and IGF-1 levels. Frasca et al. trial in hip fracture patients. Recognised as the most clinically validated GH secretagogue aside from GHRH analogs.
Where can I buy research-grade MK-677 (Ibutamoren)?
QSC stocks research-grade MK-677 (Ibutamoren) at ≥99% HPLC purity with Janoshik COA verification. Available in Oral capsules/tablets, 25mg with 5-region domestic US and international shipping.
What compounds are related to MK-677 (Ibutamoren)?
Research Use Only: All QSC products are sold strictly for in vitro laboratory research. Not for human or veterinary use. Researchers are responsible for compliance with local regulations.
