Tirzepatide: What It Is, How It Works & Research Data | QSC
QSC RESEARCH COMPOUND
Tirzepatide
Dual GIP/GLP-1 receptor agonist — the first approved dual incretin mimetic.
≥99% HPLC Purity MS Confirmed Janoshik COA Research Use Only
What is Tirzepatide?
Tirzepatide is a once-weekly synthetic peptide that simultaneously activates both GIP receptors (GIPR) and GLP-1 receptors (GLP-1R). Developed as LY3298176 — the first dual incretin receptor agonist to reach Phase 3 and approval.
How Does Tirzepatide Work?
GLP-1R activation drives insulin secretion and appetite suppression (same mechanism as semaglutide). GIPR activation in adipose tissue enhances insulin sensitivity, reduces glucagon, and may potentiate GLP-1R effects via cAMP synergy in the hypothalamus.
Key Research
SURMOUNT-1 (NEJM 2022): tirzepatide 15mg produced −20.9% body weight vs −2.4% placebo at 72 weeks — the largest Phase 3 weight reduction at time of publication.
Tirzepatide is a once-weekly synthetic peptide that simultaneously activates both GIP receptors (GIPR) and GLP-1 receptors (GLP-1R). Developed as LY3298176 — the first dual incretin receptor agonist to reach Phase 3 and approval.
How does Tirzepatide work?
GLP-1R activation drives insulin secretion and appetite suppression (same mechanism as semaglutide). GIPR activation in adipose tissue enhances insulin sensitivity, reduces glucagon, and may potentiate GLP-1R effects via cAMP synergy in the hypothalamus.
What research has been done on Tirzepatide?
SURMOUNT-1 (NEJM 2022): tirzepatide 15mg produced −20.9% body weight vs −2.4% placebo at 72 weeks — the largest Phase 3 weight reduction at time of publication.
Where can I buy research-grade Tirzepatide?
QSC stocks research-grade Tirzepatide at ≥99% HPLC purity with Janoshik COA verification. Available in Lyophilised powder, 10mg and 30mg vial kits with 5-region domestic US and international shipping.
What compounds are related to Tirzepatide?
Researchers studying Tirzepatide frequently also investigate: Semaglutide, Retatrutide, Cagrilintide, Mazdutide.
Research-Grade Tirzepatide from QSC
Available: Lyophilised powder, 10mg and 30mg vial kits | ≥99% HPLC | Janoshik COA | 5-region shipping
Research Use Only: All QSC products are sold strictly for in vitro laboratory research. Not for human or veterinary use. Researchers are responsible for compliance with local regulations.
