≥99% HPLC — why it matters for HGH research

Somatropin (191aa) is a longer peptide — synthesis yield and purity are harder to achieve than shorter peptides. At ≥99% HPLC, deletion sequences and aggregates represent <1% of total material. For in vivo GH research where dose precision and receptor specificity matter, this purity standard is the appropriate baseline.

Janoshik MS identity on 191aa peptides

For HGH (191 amino acids), mass spec identity confirmation is especially important. The theoretical MW is 22,124 Da. Janoshik MS confirmation that observed MW matches theoretical within ≤1 Da verifies that the 191-residue sequence is correctly synthesised — not a truncated fragment sold as full-length HGH. QSC provides this on every batch.

GH deficiency model — dw/dw Snell dwarf rat or GH receptor KO mouse

Classic GH deficiency model: dw/dw Snell dwarf rats lack pituitary GH. Subcutaneous HGH 0.1-1mg/kg/day × 4 weeks. Primary: body weight, IGF-1 (serum ELISA), tibia length, muscle weight (tibialis anterior, gastrocnemius). Establishes dose-response for systemic GH effects in GH-naïve animals.

Body composition research

DIO (diet-induced obese) C57BL/6. HGH Fragment 176-191 or AOD-9604 vs HGH vs vehicle. EchoMRI at baseline/4/8 weeks. Compare lipolytic (frag) vs full anabolic+lipolytic (HGH) profiles. Identifies the C-terminal lipolytic mechanism vs full GH receptor activation.

Does QSC ship HGH to the USA?

Yes — QSC ships HGH (Somatropin 191aa) and all GH-related research compounds from a US domestic warehouse. Standard delivery 3-7 business days. All orders include Janoshik COA and research documentation.

What is the difference between HGH and HGH Fragment 176-191?

HGH (191aa) is full-length somatropin — activates GHR for full anabolic + lipolytic effects (IGF-1 elevation, muscle, fat). HGH Fragment 176-191 is the C-terminal fragment — selectively activates the lipolytic mechanism without significant GHR anabolic activity or IGF-1 elevation. For fat-specific research, the fragment is the cleaner tool.

What is the purity standard for QSC HGH?

≥99% HPLC purity with Janoshik MS identity confirmation of the full 191aa sequence (22,124 Da theoretical MW). The MS identity test confirms the full-length sequence — not a truncated fragment — is present.

What GH secretagogues does QSC offer?

CJC-1295 No-DAC (GHRH analog), Ipamorelin (selective GHSR-1a), GHRP-2 (high-potency GHSR-1a), GHRP-6 (GHSR-1a + appetite), Sermorelin (GHRH 1-29), Tesamorelin (modified GHRH), Hexarelin (GHSR-1a + CD36). All ship domestically in the USA.