QSC RESEARCH GRADE
≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SPPS1-Region Domestic Shipping
What is BAM15?
BAM15 is a protonophore that dissipates the mitochondrial proton gradient — uncoupling OXPHOS from ATP synthesis and driving energy dissipation as heat. Critically, BAM15 does not penetrate the plasma membrane and does not cause hyperthermia in vivo — the primary safety limitation of classical uncouplers (DNP). Romero et al. 2020: fat mass reduction and improved insulin sensitivity in DIO mice without hyperthermia. CAS 2061936-25-0.
Research Applications
Mitochondrial Uncoupling
Proton gradient dissipation — heat vs ATP thermogenesis research
Safe Uncoupler Reference
No plasma membrane penetration — avoids DNP hyperthermia
Obesity/Metabolic
Romero 2020: fat mass reduction + insulin sensitivity in DIO mice
UCP1 Comparison
Pharmacological vs physiological (BAT UCP1) uncoupling
Mitochondrial Bioenergetics
OCR/ECAR (Seahorse), proton leak, coupling efficiency
Quick Specs
| Form | Tablet — 50mg per tablet, 100-tablet bottle |
| CAS Number | 2061936-25-0 |
| Molecular Formula | C₁₃H₁₈F₆N₂O₃ |
| Molecular Weight | 380.3 g/mol |
| Compound Type | Mitochondrial Uncoupler — Protonophore |
| Purity | ≥99% by HPLC — every batch |
| Identity | MS molecular weight confirmed — every batch |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house synthesis — Qingdao, China |
| Storage | Room temperature sealed | cool, dry storage |
| Shelf Life | 24 months unopened |
